Vacuolated neutrophils in ethanol toxicity

Role of estradiol in reducing ethanol toxicity.

Acute and sub-acute oral toxicity of ethanol extract of Cassia fistula fruit in male rats

Objective: The plantCassia fistula L. (Caesalpiniaceae) is traditionally used to treat heart diseases, abdominal pain and fever. The present study was aimed to investigate the toxic effects acute and sub-acute administration of ethanol extract of C. fistula fruit (CFE) in male Wistar rats. Materials and Methods: In acute toxicity, the effects of a single oral dose (1000, 3000 and 5000 mg/kg) of...

Effect of Nigella sativa fixed oil on ethanol toxicity in rats

Objective(s):This study was planned to appraise the protective effect of Nigella sativa fixed oil (NSO) against subchronic ethanol induced toxicity in rats. Materials and Methods: Studies were carried out on six groups of six animals each, including control (normal saline, gavage), ethanol (3 g/kg/day, gavage), NSO (0.125, 0.25 and 0.5 ml/Kg/day, IP) plus ethanol and NSO (0.5 ml/Kg/day, IP) gro...

Ethanol Toxicity in the Brain: Alteration of Astroglial Cell Function

Ethanol consumption has for a long time been associated with brain damage. Experimental studies and necropsy examinations of chronic alcoholics have shown a variety of structural and functional alterations in the neurons as well as in the glial cells. Such alterations are seen also in children with the alcoholic foetal syndrome. Ethanol is known to be a teratogen. Its abusage can result as dysf...

Exogenous Nucleotides Antagonize the Developmental Toxicity of Ethanol In Vitro

The objective of this study was to assess whether nucleotides supplementation in vitro could suppress ethanol-induced developmental toxicity in mouse. The models of whole embryo culture (WEC) and midbrain (MB) cell micromass culture were used in this study. In WEC system, exposure to 4.0 mg/mL ethanol for 48 h yielded various developmental malformations of the mice embryos. Nucleotides suppleme...